Cephalosporin podand derivatives.

نویسندگان

  • A Kovács-Kulyassa
  • P Herczegh
  • F J Sztaricskai
  • P Szabó
چکیده

work in the synthesis of podand molecules6), the present paper describes the preparation of certain podand-type trimers of cephalosporin antibiotics (Scheme 1 ). As the central block of the target trimers the tricarboxylic acid 3 was employed, which was obtained by the alkylation of phloroglucinol (1) with methyl bromoacetate and subsequent alkaline hydrolysis. The tert-butyl esters of 7-aminocephalosporanic acid (5)14) and 7pp.1207 1211

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عنوان ژورنال:
  • The Journal of antibiotics

دوره 53 10  شماره 

صفحات  -

تاریخ انتشار 2000